منابع مشابه
Cloning of Ly-5 cDNA.
A notable feature of Ly-5, among immunogenetic systems that identify glycoproteins of the cell surface and define the surface phenotype of cells according to their lineage, is that the Ly-5 locus specifies a range of molecular isoforms that distinguish cells of different stages and branches of hematopoietic development. The composition of the Ly-5 locus is of much interest in regard to how thes...
متن کاملSequences of Ly-5 cDNA: isoform-related diversity of Ly-5 mRNA.
The Ly-5 system of the mouse is expressed exclusively by hematopoietic cells and comprises a series of glycoprotein isoforms that typify different hematopoietic cell lineages. The 200-kDa isoform of T cells and the 220-kDa isoform of B cells are known to differ in peptide composition. The complete 1152 amino acid sequence of the 200-kDa isoform protein deduced from cDNA sequence appears to comp...
متن کاملCloning of the cDNA for human 5-lipoxygenase.
The enzyme 5-lipoxygenase (5-LO) catalyzes the first two reactions in the pathway leading to the formation of leukotrienes from arachidonic acid. Leukotrienes are potent arachidonic acid metabolites possessing biological activities that suggest a role in the pathophysiology of allergic and inflammatory diseases. To obtain structural information about 5-LO for use in developing anti-inflammatory...
متن کاملCloning of bovine CD34 cDNA.
CD34 is a leukocyte antigen that is expressed in various cell types including hematopoietic cells. Monoclonal antibodies against human, murine, and canine CD34 proteins have been used for the identification of lymphohematopoietic stem/progenitor cells. The cDNA encoding bovine CD34 was cloned, and its nucleotide sequence was determined. The identity of the deduced amino acid sequence of the enc...
متن کاملLecture 11 - cDNA Cloning Lab
Research Objective A researcher used differential cDNA cloning to isolate a cDNA transcripts representing growth factor induced genes. One of these cDNA clones corresponded to a previously uncharacterized open reading frame in the human genome which the exasperated researcher named "Another Moronic Gamble" (AMG). Since increased steady-state mRNA levels could be due to either transcriptional in...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1985
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.82.21.7360